Showing posts with label Hormones. Show all posts
Showing posts with label Hormones. Show all posts

Why Do Women Need Progesterone?

Menopausal women use progesterone in hormone replacement therapy, women who experience PMS (premenstrual syndrome) also respond well to natural progesterone. Progesterone is known to aid conception and is also produced through out pregnancy. Progesterone plays a lot of roles in women the chief of which is to balance the effects of estrogen, if estrogen is not checked it results in the symptoms listed under estrogen dominance. During menopause the level of progesterone may drop to almost zero in some women while that of estrogen drops to about 40-60% which is still okay to put an end to the menstrual cycle. The use of progesterone after menopause would help to argument the overall hormone balance, because progesterone is the precursor to a lot of steroid hormones.

Menopause Hormone Therapy

Postmenopausal women and physicians should no longer fear hormone. The Society of Obstetricians and Gynecologists of Canada (SOGC) released yesterday its new clinical guidelines on menopause. According to the SOGC, took the hormone for less than five years are harmless and can instead help women get rid of troublesome symptoms such as hot flashes.

By publishing these guidelines, the SOGC has sought to silence the belief that hormones increase the risk of breast cancer and cardiovascular disease in post menopausal women.


In 2001, a study conducted in the United States had shown that after four years of hormone therapy, breast cancer increased by 26% in postmenopausal women. With the publication of this study, more than 50% of Americans have stopped their treatment.


SOGC analyzed data available to determine whether the hormone is so harmful. "We have noticed that the 2001 study was conducted mainly on women aged 60 to 70 years. The average age was too high! Especially when we know that age is the main risk factor for breast cancer and cardiovascular disease, "says the director of the division of reproductive endocrinology and infertility at Queen's University, Dr. Robert Reid .

"We put women in front of exaggerated fears. Women were afraid, "says professor of obstetrics and gynecology at Laval University, Dr. Michel Fortier.

According to the SOGC, postmenopausal women who want to avoid bothersome symptoms should first change their lifestyle. Control weight, smoking and level of exercise is essential.

Dr Reid acknowledged that this method is beneficial for women with symptoms means. For those with strong symptoms, hormone therapy taken in the short term is a safe and viable option, "said Dr. Reid.

85% to 95% of women see their symptoms with reduced hormone. The risk of fractures related to osteoporosis as well as the risks of suffering from vaginal drying declining.

If the hormone is less than five years, the health risks are invalid, says the SOGC. If the treatment lasts for more than five years women see their risk of contracting breast cancer increased slightly. "The risk is greater for women who are obese or who smoke," said Dr. Reid.

Increased risk among women who gave birth after age 30

According to him, should be more concerned that mothers are becoming older. Studies have shown that mothers who had their first pregnancy after age 30 are more likely to suffer from breast cancer. A third of breast cancer could be eliminated if these factors were controlled.

As to the effects of hormone therapy on cardiovascular disease and stroke, the SOGC believes they are void. We know that the hormones slightly increased risk of clots in the legs. "But in this case, age is a risk factor even more important that the hormones," said Dr. Fortier.

As for the effect of hormones on memory, studies are contradictory. According to Dr. Fortier, only younger women will have their memory improve with treatment. "But we still can not recommend hormone therapy to treat Alzheimer's disease," said Dr. Fortier.

Zoom Into Perimenopause Changes

Menopause does not suddenly happen. It is preceded by a long period known as perimenopause. This period of menstrual irregularities preceding the termination of period and the years following the apparent arrest of the menstrual cycle.

Between 45 and 50 years menstrual abnormalities beginning to appear, this age varies depending on heredity and gynecological history.

Disturbances annunciator

This period preceding the end of your menstrual cycle and last from two to four years.

Corresponding to the declining production of female hormones, it is marked by menstrual irregularities

  • Lengthening or shortening of the cycle;
  • Change of abundance, frequency and duration of the the menstrual period.

Troubles before your menstrual period (or premenstrual syndrome congestif):

  • Tension breasts swollen and painful (mastodynie);
  • Abdominal bloating
  • Instability of mood
  • Insomnia
  • Edema in the face, etc..

The uterus is a bit much bigger. The cervical mucus is abundant. These symptoms are related to the persistence or exaggeration of the secretion of estrogen and decrease (or disappearance) secretion of progesterone.

Perimenopause lasts four years on average and by definition continues during the 12 months following the latest menstrual period, in events that this don’t pose big problems, no treatment is necessary. However, if the troubles really hamper the quality of life, you should talk with your doctor. With him, the possibility of treatment can be addressed.

Menopause And Hormone During Women Life Stages

Puberty, perimenopause, menopause, post-menopause ... The women life is physiological marked with different changes. While hormones play an important place in our daily lives, what do you know exactly about these substances?

If you thought that only teenagers are governed by their hormones, know that this influence continues throughout your life too.

The four stages of hormonal life

The female body changes with age and many of these changes are directly related to hormones influence, this rate varies during different stages of life. The influence of hormones is dormant during childhood and they start between 9 and 13 years.

Puberty: The breasts begin to form (breast bud). The pubic hair appear and between one and four years later, come the first period that mark the entrance into puberty. This period ends with the complete maturation of genitals.

Perimenopause: This transition reflects the approach of menopause. The period become less regular and the first symptoms of menopause may appear (hot flashes, night sweats ...). This period is between 2 and 4 years before the latest rules and is still one year after stopping them.

Menopause: Entering menopause is marked by the latest rules. Nobody knows with certainty that this is the last after a year without menstruation.

Post-menopause: the period after menopause and continues until the end of life. Pregnancies are impossible.

But what are the mysterious conductors that punctuate the lives of women?

The secrets circuits of hormonal system

Without claiming to explain all the hormonal mechanisms of our body, i will present some highlights. In this hormonal system, several bodies take the spotlight.

The ovaries are two small oval bodies located on both sides of the uterus. At birth, they contain 700 000 follicles. Only 400 to 500 of them will be matured and bond actually an egg during the menstrual cycle. The maturation of these follicles is linked to the production of estrogen.

But the real conductor of this system lies in the head. At the base of the brain, the hypothalamus is a small gland, this is the key to the whole system. Stimulated by the central nervous system, stimulates the hypothalamus, pituitary hormones through Gn RH. In turn, the front part of the pituitary hormone follicular stimulation product (FSH) and the luteinizing hormone (LH). Acting together, these two hormones in turn stimulate the maturation of one of ovarian follicles, which will give an egg. As the maturation of the egg, the quantities of estrogen and progesterone increase. These hormones will cause the thickness of the uterine epithelium, which is preparing to welcome and nurture the fertilized egg after conception. The maximum rate of estrogen is reached a day before ovulation. It is the LH hormone that triggers ovulation around the 14th day. Caution, however, this can vary so contraceptive methods based on this schedule are not reliable. If there is no fertilization, the hormone levels fall, the uterine wall is necrosis, is off and the period are triggered while rebuilding the wall is being .

With the approach of perimenopause, the hormone levels fluctuate without following any rhythm. On the other hand, the pituitary gland release more FSH hormone to maintain the smooth functioning of ovaries, which themselves become resistant to this hormone. The period become unpredictable, both in pace and their volume. Your doctor can then prescribe you the FSH. But the rate of this hormone is very volatile during perimenopause. After the absence of your menstrual period for a year and with a high rate of FSH, it can diagnose menopause. Attention, less than a year after the last menstrual period, getting pregnant is always possible.

Hormonal Treatment Of Menopause

Risks demonstrated ... in 2002, the publication of a U.S. study called WHI (for Women's Health Initiative) was the effect of a thunderclap in the sky for the treatment of menopause. Since European and French, study have prompted health authorities to revise on downwards the guidance of hormonal treatment of menopause. But specifically, what attitude to adopt towards treatment when a woman is experiencing menopause

Tailor the treatment

"Today, treatment are reserved primarily for women suffering from climacteric, ie hot flashes, joint pain, from vaginal dryness, etc.. They take "sometime", time disturbances, generally 4 to 5 years. And the ideal combination of hormones is an estrogen administered through the skin (patch or gel) that adding natural progesterone (Utrogestan or the one of its generic tablets). " Another proposal experts, the tibolone (Livial), a hormone replacement therapy for menopause alone to estrogen and progestin effects at the same time, effective bursts of heat and the bone without the disadvantages of hormone replacement therapy ( TSH) "classic" on the breast.

What is the real risk?

The Strategy of HRT is based on the results of a number of studies. Thus, hormones surrogates are taking a risk of phlebitis and / or pulmonary embolism which we know are due to estrogen take tablets. Then heart disease, which are linked to the type of progestin: "The molecule chosen by the Americans is very little used in France for example"

Finally, the third risk is breast cancer, confirmed by all studies. But it seems that the TSH reveals cancer rather than creates it, and ultimately, the mortality rate is the same as taking HRT or not. Perhaps it would be even better prognosis when receiving HRT because their breast cancers are different and / or they are better used on ... What is certain is that women who don ' have not received progestin, because their uterus was removed in the past did not have breast cancer. And two hormones, natural progesterone and tibolone, have proved so far without any disadvantage for the breast. The second is also tested for 3 years in the "worst" conditions, in women who have had breast cancer.

Finally, if we analyse all recent work, the treatment of menopause would have a positive effects when it is given just after menopause, not after 60 years, as was the case in the WHI study TSH which was administered to prevent the consequences of aging.